SBNO1, strawberry notch homolog 1, 55206

N. diseases: 39; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.100 GeneticVariation phenotype GWASCAT Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. 31420334 2019
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker disease BEFREE SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus. 11511096 2001
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement
0.100 GeneticVariation phenotype GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
CUI: C0428472
Disease: Serum HDL cholesterol measurement
Serum HDL cholesterol measurement
0.100 GeneticVariation phenotype GWASDB Discovery and refinement of loci associated with lipid levels. 24097068 2013
CUI: C0428472
Disease: Serum HDL cholesterol measurement
Serum HDL cholesterol measurement
0.100 GeneticVariation phenotype GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.300 Biomarker disease CTD_human Increased exonic de novo mutation rate in individuals with schizophrenia. 21743468 2011
CUI: C2973725
Disease: Pulmonary arterial hypertension
Pulmonary arterial hypertension
0.010 Biomarker disease BEFREE A novel S-nitrosocaptopril monohydrate for pulmonary arterial hypertension: H<sub>2</sub>O and -SNO intermolecular stabilization chemistry. 30227269 2018
CUI: C0032269
Disease: Pneumococcal Infections
Pneumococcal Infections
0.010 AlteredExpression group BEFREE Genetic ablation of the clock gene Bmal1 (also called Arntl or MOP3) in bronchiolar cells disrupts rhythmic Cxcl5 expression, resulting in exaggerated inflammatory responses to lipopolysaccharide and an impaired host response to Streptococcus pneumoniae infection. 25064128 2014
Parkinson Disease 6, Autosomal Recessive Early-Onset
0.010 Biomarker disease BEFREE SNO-PINK1 decreases Parkin translocation to mitochondrial membranes, disrupting mitophagy in cell lines and human-iPSC-derived neurons. 29166608 2017
PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE
0.010 Biomarker disease BEFREE SNO-PINK1 decreases Parkin translocation to mitochondrial membranes, disrupting mitophagy in cell lines and human-iPSC-derived neurons. 29166608 2017
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.030 Biomarker disease BEFREE Moreover, we detect SNO-PTEN in human brains with sporadic PD. 25378175 2014
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.030 Biomarker disease BEFREE We observed increased SNO-Prx2 in human Parkinson's disease (PD) brains, and S-nitrosylation of Prx2 inhibited both its enzymatic activity and protective function from oxidative stress. 18003920 2007
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.030 AlteredExpression disease BEFREE We first showed that SNO-Parkin reduced its ability as a suppressor of Drp1 expression, leading to upregulation of Drp1 in neurotoxin-based PD models, in vitro and in vivo. 27267045 2016
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee
0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee
0.400 Biomarker disease CTD_human Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee
0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.010 Biomarker disease BEFREE Copy numbers of EVI1 and TERC increased more than those of SNO and PIK3CA in our panel of NSCLC cell lines. 14581340 2003
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders
0.010 Biomarker group BEFREE 'SNO'-Storms Compromise Protein Activity and Mitochondrial Metabolism in Neurodegenerative Disorders. 29097102 2017
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.010 Biomarker disease BEFREE Here, we found that S-nitrosylation of O-linked N-acetylglucosaminyltransferase (SNO-OGT) was induced by β-amyloid peptide (Aβ) exposure to SK-N-MC and SK-N-SH human neuroblastoma cells. 26854602 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE To discuss the role of survivorship care and survivorship care plans, including a recently developed neuro-oncology-specific plan care (https://www.soc-neuro-onc.org/SNO/Resources/Survivorship_Care_Plan.aspx) for adult patients diagnosed with primary glial neoplasms and the necessary educational needs of oncology nurses. 30446382 2018
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions
0.010 Biomarker disease BEFREE This study confirmed that the TPZ/HMTNPs-SNO with multi-mechanisms exploited the merits of synergistic combination of the three therapeutic modes, consequently potentiating the anticancer efficacy of SDT. 29474964 2018
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.030 Biomarker disease BEFREE We investigated the antiproliferative effects of AuNP synthesized from MO aqueous leaf extracts (MLAuNP ) in A549 lung and SNO oesophageal cancer cells. 26923760 2016
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.030 GeneticVariation disease BEFREE This study investigated FA-induced cytotoxicity and apoptotic induction in the SNO OC cell line. 27956242 2017
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.030 Biomarker disease BEFREE A Comparison of the Toxicity of Mono, Bis, Tris and Tetrakis Phosphino Silver Complexes on SNO Esophageal Cancer Cells. 28530542 2018